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Agenda - September 23 Webinar

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Webinar on Multimodal Therapy for Esophageal Cancer

The best of the best free papers submitted for ISDE 2020 will be featured across three ISDE webinars. In the first of these 9 free papers that each address a cutting edge issue relevant to the management of esophageal cancer will be presented. From novel basic research to the outcomes of practice changing randomized trials these papers will deliver the information you need to stay abreast of the field. Complementing the free papers, Professor John Reynolds will deliver a state of the art update on multimodal therapy for esophageal cancer from the perspective of the practicing surgeon. This 2 hour focused webinar will deliver what you need to keep your esophageal cancer practice up to date.

After attending this event, the participant should be able to state the correct use of surgery, chemotherapy and radiotherapy for cancerous conditions of the esophagus.

Register for On-Demand Access

September 23, 2020 at 7am in New York / 12pm in London / 1pm in Paris / 8pm in Tokyo / 9pm in Sydney
Duration: 120 minutes

Chair: David Watson, Flinders University, Australia
Co-chair/Moderator: Philip Chiu, The Chinese University of Hong Kong, Hong Kong
Co-chair/Moderator: John Reynolds, St. James’s Hospital, Ireland

  1. Cancer Cells Persist after Complete Pathological Response in Esophageal Adenocarcinoma - Rob Walker, University of Southampton, Southampton General Hospital, UK (7 minutes + Q&A 3 mins)
  1. Genomic Analysis of Response to Neoadjuvant Chemotherapy in Esophageal Adenocarcinoma - Fereshteh Izadi, University of Southampton, Southampton General Hospital, UK (7 minutes + Q&A 3 mins)
  1. Volatile Organic Compound Profiling for Detection of Esophageal Cancer in Exhaled Breath – Ravi Vissapragada, Flinders University, Australia (7 minutes + Q&A 3 mins)
  1. Visualisation of Thoracic Duct During Esophagectomy by Real-time Fluorescent Imaging - A Technique in Evolution - Subramanyeshwar Rao Thammineedi, Basavatarakam Indoamerican Cancer Hospital, India (7 minutes + Q&A 3 mins)
  1. 10-year Follow-up of a Randomised Controlled Trial Comparing Neoadjuvant Chemoradiotherapy plus Surgery Versus Surgery Alone for Oesophageal Cancer (CROSS) - Ben Eyck, Erasmus MC - University Medical Center Rotterdam, The Netherlands (7 minutes + Q&A 3 mins)
  1. Surgical Morbidity and Mortality from the Neoresii Trial: Standard Vs. Prolonged Time to Surgery after Neoadjuvant Chemoradiotherapy for Esophageal Cancer – Klara Nilsson, Karolinska University Hospital, Sweden (7 minutes + Q&A 3 mins)
  1. Chemoradiotherapy Followed by Active Surveillance Versus Surgery for Esophageal Cancer: A Systematic Review and Individual Patient Data Meta-analysis – Berend Van Der Wilk, Erasmus MC – University Medical Center, The Netherlands (7 minutes + Q&A 3 mins)
  1. Definitive Chemoradiotherapy Compared to Neoadjuvant Chemoradiotherapy with Esophagectomy for Loco-regional Esophageal Cancer: National Population-based Cohort Study - Sivesh Kathir Kamarajah, Royal Victoria Infirmary, UK (7 minutes + Q&A 3 mins)
  1. Length of Hospital Stay and the Association with Readmission after Uncomplicated Esophagectomy. Significant Hospital Variation in the Netherlands - Daan Michiel Voeten, Amsterdam University Medical Center, The Netherlands (7 minutes + Q&A 3 mins)
  1. Invited Lecture: Multimodal Therapy for Esophageal Cancer – a Surgeon’s Perspective - Prof John Reynolds, St. James’s Hospital, Ireland (15 minutes)
  1. Discussion (15 minutes)

Speakers

Ben Eyck
PhD student, Department of Surgery, Erasmus MC, University Medical Centre, Netherlands

Ben Eyck

Fereshteh Izadi
University of Southampton, Southampton General Hospital, UK

Fereshteh Izadi

Sivesh Kamarajah
NIHR Academic Clinical Fellow, General Surgery, University Hospital Birmingham NHS Trust, UK

Sivesh Kamarajah

Klara Nilsson
PhD Student, General Surgery, Karolinska University Hospital, Sweden

Klara Nilsson

John V. Reynolds
Clinical Surgery, St. Jame's Hospital & Trinity College Dublin, Ireland

John V. Reynolds

Subramanyeshwar Rao Thammineedi
Director & Chief Surgical Oncologist, Indo-American Cancer Hospital, Hyderabad

Subramanyeshwar Rao Thammineedi

Berend van der Wilk
Surgery in Erasmus MC, University Medical Center, USA

Berend van der Wilk

Ravi Vissapragada
General Surgical Trainee, Australia

Ravi Vissapragada

Daan M Voeten
PhD Candidate, Dutch Institute for Clinical Auditing, Amsterdam

Daan M Voeten

Rob Walker
Esophago-gastric Surgical Trainee, University of Southampton, UK

Rob Walker

Ben Eyck

PhD student, Department of Surgery, Erasmus MC, University Medical Centre, Netherlands

Ben Eyck

Ben Eyck is MD, PhD student at Dept. of Surgery of the Erasmus MC - University Medical Centre in Rotterdam, the Netherlands. His PhD thesis focuses on neoadjuvant treatment, active surveillance after neoadjuvant treatment, and surgical treatment for esophageal cancer.

Fereshteh Izadi

University of Southampton, Southampton General Hospital, UK

Fereshteh Izadi

Fereshteh Izadi completed a PhD in comparing gene regulatory networks by microarray and RNA-seq in July 2017. Shortly after she started her first postdoctoral job in University College London as a bioinformatician on single cell RNA-seq data analysis. Afterwards she started her second job at University of Southampton working on multi omics data analysis in oesophageal adenocarcinoma.

Sivesh Kamarajah

NIHR Academic Clinical Fellow, General Surgery, University Hospital Birmingham NHS Trust, UK

Sivesh Kamarajah

Sivesh Kamarajah is currently an NIHR Academic Clinical Fellow in General Surgery at University Hospital Birmingham NHS Trust. He is currently steering committee member for the Student Audit and Research in Surgery (STARSurg) National Collaborative, the International, multicentre prospective cohort study, Oesophagogastric Anastomosis Audit (OGAA), and the CovidSurg Collaborative.

Klara Nilsson

PhD Student, General Surgery, Karolinska University Hospital, Sweden

Klara Nilsson

Klara Nilsson is a PhD student at Karolinska Institute and 5th year resident in general surgery at Karolinska University Hospital. Her academic work is mainly focused on the timing of surgery after neoadjuvant chemoradiotherapy in the treatment of esophageal cancer.

John V. Reynolds

Clinical Surgery, St. Jame's Hospital & Trinity College Dublin, Ireland

John V. Reynolds

Professor Reynolds is Professor of Clinical Surgery at the St. James’s Hospital and Trinity College Dublin. He is the National Lead for oesophageal and gastric cancer. He is Cancer Lead at St. James’s Hospital and the Trinity School of Medicine, and a Principal Investigator in the Trinity Translational Medicine Institute. He has formerly held Fellowship positions with the University of Pennsylvania and Wistar Institute in Philadelphia and at the Memorial Sloan-Kettering Cancer Centre in New York. He was a Senior Lecturer at St. James’s University Hospital in Leeds (1994-6). Professor Reynolds has obtained numerous research awards and has published widely in cancer research, with over 250 publications and approximately €5m research grant income. His clinical interest is in diseases of the oesophagus and stomach. His research interest is in four areas: (1) pathogenesis of Barrett’s oesophagus and progression; (2) prediction of response and resistance to chemotherapy and radiation therapy.

Subramanyeshwar Rao Thammineedi

Director & Chief Surgical Oncologist, Indo-American Cancer Hospital, Hyderabad

Subramanyeshwar Rao Thammineedi

M.S (Gen. Surgery ), M.Ch(Surgical Oncology

Professional positions:

Formerly: Professor of Surgical Oncology, Osmania Medical College, Hyderabad
Presently: Director & Chief Surgical Oncologist, Indo-American Cancer Hospital, Hyderabad

Organisational positions:
Past Secretary – Indian Association of Surgical Oncology
Past President - ASI Telangana
Vice President - Hyderabad Surgeons Society
Chief Patron - Hockey Warangal

Author of 84 Publications.
Reviewer: Journals in Surgical Oncology, Gynecologic Oncology and Thoracic Oncology

Berend van der Wilk

Surgery in Erasmus MC, University Medical Center, USA

Berend van der Wilk

Berend van der Wilk is a PhD candidate at the department of Surgery in Erasmus MC - University Medical Center. He is one of the coordinators of the randomized SANO-trial (Surgery As Needed for Oesophageal cancer). His promotor is prof. dr. JJB van Lanschot.

Ravi Vissapragada

General Surgical Trainee, Australia

Ravi Vissapragada

Ravi Vissapragada is a general surgical trainee from Adelaide, Australia. He is currently pursuing a Ph.D. from Flinders University. His research interests are in detection of Barrett's Esophagus and Esophageal cancer in Volatile Organic Compounds in exhaled breath and improving cost-effectiveness of endoscopic surveillance of Barrett's Esophagus.

Daan M Voeten

PhD Candidate, Dutch Institute for Clinical Auditing, Amsterdam

Daan M Voeten

Daan M Voeten is a PhD candidate at the Dutch Institute for Clinical Auditing and the Amsterdam University Medical Center under the supervision of Prof. Dr. Van Berge Henegouwen and Prof. Dr. Van Hillegersberg. The main focus of his work is assessment of quality of Dutch surgical upper gastrointestinal care at the Dutch Upper Gastrointestinal Cancer Audit (DUCA).

Rob Walker

Esophago-gastric Surgical Trainee, University of Southampton, UK

Rob Walker

Rob Walker is a Cancer Research UK Clinical Research Fellow and esophago-gastric surgical trainee at the University of Southampton, UK. Working under the mentorship of Professor Tim Underwood, he is completing a PhD on the tumor micro-environment in esophageal adenocarcinoma. His research focusses on single cell RNA sequencing to detect rare cell types and interpreting the cell-cell interactions. He has published on both the molecular biology and clinical management of esophageal cancer and was awarded the British Journal of Surgery prize paper at the Association of Upper Gastrointestinal Surgery (AUGIS) congress in 2019 for his research.



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